which is the strangest pair you've seen in any anime?

Probably Setsuna and Sara from Angel Sanctuary

Tarou and Mariel from Hanaukyo Maids. one is shorter and the other is taller.

Don't know if this qualifies but a here goes

Kiba & Chesa from Wolf's Rain
He's a dog and she's a flower girl

an odd Canon couple??
wouldn't it be Megami and (whatever his name is..) from Ah. My Goddess??
Goddess and Mortal, they usually don't mix so well..

Inuyasha and Kikyo
I think their odd

I would say Ito and Makoto (from Hana to Yume or W Juliet, how ever you call it). Theire like switched! The girl loks like a boy and the boy is disguised as girl!

I say ummm...Robin and Amon from witch hunter robin.

Quote by NerikoI say ummm...Robin and Amon from witch hunter robin.

I second that ... if you can really consider them a couple anyway

Any couple in ranma, those guys are constantly changing form!

Sailor Uranus and Sailor Neptune